The global chromogenic substrate market is growing at a speedy rate. Growing number of research laboratories across the world with increase in funding from private and government organizations to boost research in the healthcare sector is the crucial factor that is fostering growth of the market. Furthermore, some of the key factors that are propelling the growth of the global market include growing prevalence of microbial infections, increase in use of chromogenic substrate technology in clinical laboratory for diagnostic purpose, and increase in the study on fibrinolytic & blood clotting enzymes. In 2019, there were several infectious disease outbreaks some of which includes outbreak of multidrug-resistant Salmonella in the US; measles a vaccine-preventable disease made a huge comeback in various countries, and in August 2019, the Department of Health, Philippines declared the nation’s dengue outbreak as a national epidemic after more than 622 associated deaths and 162,000 cases were reported in the first 7 months.. In addition to this, according to CDC, more than 2.8 million antibiotic resistant infections occur annually in US and over 35,000 people die due to such infections. Such huge prevalence of diseases leads to socioeconomic burden. Chromogenic substrates in such cases have proved to be a powerful tool in identification of microorganisms owing to its ability to detect specific enzymes produced by the target microorganism. These enzymes split the chromogenic substrate and produces color and points up the microorganism by color differentiation. This may help in the microbial study and lead to the development of effective treatment against microbial infections. All such factors coupled with the benefits delivered by chromogenic substrates such as cost-efficient working process, easy microbial identification & detection by means of color, and enhanced accuracy are fueling the growth of the global market. Additionally, the expanding use of chromogenic substrate in food testing in food microbiology labs is equally contributing to the growth of the overall market. Moreover, new product launches, adoption of business strategies such as collaborations, merger & acquisitions to expand the product portfolio by major players are also fueling the growth globally. . Furthermore, increasing number of chronic diseases among geriatric population coupled with emergence of new diseases has triggered the diagnostic research in microbiology field which may open several opportunities for the growth of the global chromogenic substrate market during the forecast period.
The onset of COVID-19 pandemic has moderately affected the overall market growth. The market is experiencing lag due to reduced patient visits to the hospital this is directly affecting the frequency of diagnostic test which in turn is affecting the demand for chromogenic substrate. However, with the return to pre pandemic conditions the market is expected to register healthy growth over the forecast period.
The global chromogenic substrate market is categorized based on type and application. Different types of chromogenic substrates are used in several sectors around the world. The market is categorized into types as Factor Xa Substrate, Kallicrein Substrate, Factor IXa Substrate, etc.. Various applications of chromogenic substrates in diagnostics & clinical labs, food microbiology labs, biotechnology labs, academic & research centers, and others are categorized into the report.
The chromogenic substrate market is fragmented. Major players in the global chromogenic substrate market are focusing on organic growth strategies such as mergers & acquisitions and new product launch to expand their business. Some of the major players operating in the market include Thermo Fisher Scientific Inc., Diapharma Group, Inc., Merck KGaA, Roche Diagnostics International Ltd., Santa Cruz Biotechnology, Inc., Enzo Life Sciences, Inc., CRYOPEP, Aniara Diagnostica, PerkinElmer Inc., and MOLECULAR INNOVATIONS, INC. among others.
Future tends/developments
- In June 2021, Aniara Diagnostica announced the availability of Biophen Anti-Xa and Biophen Anti-IIa, two-stage Chromogenic Assays.
- In March 2021, Roche announced launch of DISCOVERY Green HRP chromogen detection kit to expand immunohistochemistry multiplexing in cancer research.
- In May 2019, Roche expands partnership with Bio-Techne to offer drug discovery researchers new chromogenic detection options for mRNA ISH tissue analysis.
